Atrium ‐specific ion channels in the zebrafish – a role of IKACh in atrial repolarization

ConclusionWe demonstrate that the acetylcholine‐activated inward rectifying current (IKACh) current plays a major role in the zebrafish atrium, and that the zebrafish could potentially be a cost‐effective and reliable model for pharmacological testing of atrium specific IKACh modulating compounds.This article is protected by copyright. All rights reserved.

Source: Acta Physiologica - February 1, 2018 Category: Physiology Authors: Mark A. Skarsfeldt, Sofia H. Bomholtz, Pia R. Lundegaard, Angelica Lopez ‐Izquierdo, Martin Tristani‐Firouzi, Bo Hjorth Bentzen Tags: Regular Paper Source Type: research