Kinetics of viral load and cytokines in severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious viral disease in China, Japan, and Korea. The SFTS virus (SFTSV) belongs to the genus Phlebovirus of the family Bunyavirus and was first identified by a group of Chinese medical researchers [1]. The major clinical signs and symptoms of SFTS are fever, abdominal pain, vomiting, nausea, thrombocytopenia, and leukocytopenia. Multiple organ failure can sometimes occur, with a mortality rate of 6 –30% [1–3]. A previous study that used a pathogenic mouse model of SFTS reported that the viral RNA was detected and enriched primarily in the spleen during the acute phase of the disease.

Source: Journal of Clinical Virology - February 3, 2018 Category: Virology Authors: Ji-Soo Kwon, Min-Chul Kim, Ji Yeun Kim, Na-Young Jeon, Byung-Han Ryu, Jeongmin Hong, Min-Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim Source Type: research