8DSS peptide induced effective dentinal tubule occlusion in vitro

Dentin hypersensitivity is a common dental problem with a prevalence of 15 –25% in the general population [1]. It is characterized as transient acute pain associated with thermal, chemical, mechanical and osmotic stimuli. It has been confirmed that opened dentinal tubules, dentin permeability and dentin hypersensitivity are in close relationship according to the hydrodyn amic hypothesis [2], which is the most accepted theory to explain the mechanism of dentin hypersensitivity. Under the condition of dentin hypersensitivity, dentinal tubules are often open with an enlargement of the diameter, which result in an increase in dentin permeability [2].

Source: Dental Materials - February 3, 2018 Category: Materials Science Authors: Kunneng Liang, Shimeng Xiao, Hongling Liu, Wenyuan Shi, Jianshu Li, Yuan Gao, Libang He, Xuedong Zhou, Jiyao Li Source Type: research