P63 expression plays a role in developmental rate, embryo size, and local morphogenesis

CONCLUSIONS: The software atlas technique described the p63‐/‐ phenotype as a combination of developmental delay (i.e., heterochrony) and malformation (i.e., pathological shape; failed organogenesis). This study identifies for the first time global and local roles for p63 in prenatal growth and development. This article is protected by copyright. All rights reserved.

Source: Developmental Dynamics - February 1, 2018 Category: Molecular Biology Authors: Julia C. Boughner, Matthijs C. van Eede, Shoshana Spring, Lisa X. Yu, Nasim Rostampour, R. Mark Henkelman Tags: Patterns & Phenotypes Source Type: research