The Role of an Esterified Hyaluronic Acid Matrix in Wound Healing, a Case Series

Hyaluronic acid (HA) is an anionic, non-sulfated glycosaminoglycan, present throughout various tissues in the body, including connective and epithelial tissues. As part of the extracellular matrix (ECM), HA plays an essential role in the migration and proliferation of cells as well as in tissue hydrodynamics. 1 It interacts with a number of cell receptors, including CD44, receptor for HA-mediated motility (RHAMM) and intercellular adhesion molecule-1 (ICAM-1).2 Due to the various cellular interactions of HA, it has a various roles throughout each stage of wound healing.

Source: Journal of the American College of Certified Wound Specialists - February 2, 2018 Category: Dermatology Authors: Richard Simman Source Type: research