Synthesis and characterization of Ciprofloxacin-containing divinyl oligomers and assessment of their biodegradation in simulated salivary esterase

More than half of the estimated 500 million direct dental restorations placed annually worldwide are resin composites [1]. The growing interest in resin composites has been driven primarily by their superior aesthetics, ease of polymerization and facile handling. Despite the extensive use of resin composites, the resultant restorations lack the durability and chemical stability of amalgam fillings in the oral cavity [2]. This is primarily due to the inherent susceptibility of the ester linkages (which are introduced upon coupling of the methacrylate moiety) to chemical hydrolysis.

Source: Dental Materials - February 2, 2018 Category: Materials Science Authors: Yasaman Delaviz, Mitchell A. Nascimento, Michael W. Laschuk, Timothy W. Liu, Meilin Yang, J. Paul Santerre Source Type: research