Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation

To identify genetic variants associated with complement activation, which may help to select age-related macular degeneration (AMD) patients for complement-inhibiting therapies.

Source: Ophthalmology - February 1, 2018 Category: Opthalmology Authors: Laura Lor és-Motta, Constantin C. Paun, Jordi Corominas, Marc Pauper, Maartje J. Geerlings, Lebriz Altay, Tina Schick, Mohamed R. Daha, Sascha Fauser, Carel B. Hoyng, Anneke I. den Hollander, Eiko K. de Jong Source Type: research