Constitutive modeling of compressible type-I collagen hydrogels

Collagen is a naturally occurring polymer that provides a low immunogenic and biologically compatible platform for cellular attachment [1,2]. Type-I collagen, the most abundant of the collagens, endows a diverse group of mammalian tissues with their mechanical properties [3,4]. This material can be processed from primary tissue sources into acidic solutions, molded into a variety of shapes, and reconstituted into gels using pH neutralization [5]. As such, its applications in biomedical engineering are vast.

Source: Medical Engineering and Physics - February 1, 2018 Category: Biomedical Engineering Authors: Brooks A. Lane, Katrina A. Harmon, Richard L. Goodwin, Michael J. Yost, Tarek Shazly, John F. Eberth Source Type: research