Neurodegenerative diseases: Inflammasome protein seeds plaques in Alzheimer disease

Nature Reviews Drug Discovery 17, 96 (2018). doi:10.1038/nrd.2018.5 Author: Megan Cully Alzheimer disease is characterized by the presence of amyloid-β (Aβ) plaques in the brain (which are thought to cause neuronal dysfunction), as well as by neurochemical changes and inflammation. Writing in Nature, Venegas and colleagues found that aggregates of apoptosis-associated speck-like protein containing a
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research