Promoter polymorphisms in TGF ‐®1 and IL‐10 genes influence tumor dendritic cells infiltration, development and prognosis of colorectal cancer

ConclusionThe T‐allele of TGFB1 ‐509C/T SNP might be a protective factor for development of CRC, but in the course of the disease this variant allele might be associated with more unfavorable prognosis of the patients.

Source: The Journal of Gene Medicine - January 1, 2018 Category: Genetics & Stem Cells Authors: Maya Gulubova, Elina Aleksandrova, Tatyana Vlaykova Tags: RESEARCH ARTICLE Source Type: research