[Articles] Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis

Continuation of treatment beyond progression in the product labelling of these immunotherapies has not been recommended because the clinical benefit remains to be proven. Treatment beyond progression with anti-PD-1 antibody therapy might be appropriate for selected patients with unresectable or metastatic melanoma, identified by specific criteria at the time of progression, based on the potential for late responses in the setting of the known toxicity profile.

Source: The Lancet Oncology - January 17, 2018 Category: Cancer & Oncology Authors: Julia A Beaver, Maitreyee Hazarika, Flora Mulkey, Sirisha Mushti, Huanyu Chen, Kun He, Rajeshwari Sridhara, Kirsten B Goldberg, Meredith K Chuk, Dow-Chung Chi, Jennie Chang, Amy Barone, Sanjeeve Balasubramaniam, Gideon M Blumenthal, Patricia Keegan, Richa Tags: Articles Source Type: research