[Comment] Inotuzumab ozogamicin in older patients with acute lymphoblastic leukaemia: premises and promises

Outcomes obtained with conventional chemotherapy treatments in patients with newly diagnosed acute lymphoblastic leukaemia worsen as age increases, with children displaying the most favourable end results and older patients the worst. Worse outcomes in older patients with acute lymphoblastic leukaemia are attributed to frequent presence of comorbidities, poor tolerance to intensive chemotherapy, and the different biological characteristics of acute lymphoblastic leukaemia at an older age, often displaying dissimilar patterns of sensitivity towards traditional chemotherapy agents.
Source: The Lancet Oncology - Category: Cancer & Oncology Authors: Tags: Comment Source Type: research