Reversal of visceral hypersensitivity in rat by Menthacarin ®, a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation

Conclusions & InferencesThe development of visceral hypersensitivity in maternally separated rats and the Menthacarin®‐mediated reversal of hypersensitivity is associated with changes in the mycobiome. Therefore, Menthacarin® may be a safe and effective treatment option that should be tested for IBS. The gut fungal microbiome (mycobiome) was recently identified as a possible cause for abdominal pain in IBS. We showed that a peppermint‐ and caraway‐oil‐preparation with fungicidal activity, called Menthacarin®, can reverse mycobiome‐dependent visceral hypersensitivity in rat.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fnmo.13299

Source: Neurogastroenterology and Motility - January 31, 2018 Category: Gastroenterology Authors: S. Botschuijver, O. Welting, E. Levin, D. Maria ‐Ferreira, E. Koch, R. C. Montijn, J. Seppen, T. B. M. Hakvoort, F. H. J. Schuren, W. J. de Jonge, R. M. van den Wijngaard Tags: ORIGINAL ARTICLE Source Type: research