The role of the AR/ER ratio in ER-positive breast cancer patients

In conclusion, the AR/ER ratio ≥2 identifies a subgroup of patients with aggressive biological features and may represent an additional independent marker of worse BC prognosis. Moreover, the Prosigna-PAM50 results indicate that a significant number of cases with AR/ER≥2 could be non-luminal tumours.

Source: Endocrine-Related Cancer - January 31, 2018 Category: Endocrinology Authors: Rangel, N., Rondon-Lagos, M., Annaratone, L., Osella-Abate, S., Metovic, J., Mano, M. P., Bertero, L., Cassoni, P., Sapino, A., Castellano, I. Tags: Research Source Type: research