Ablation of PPAR γ in subcutaneous fat exacerbates age‐associated obesity and metabolic decline

In conclusion, our study uncovers an essential role for PPARγ in maintaining energy expenditure during the aging process and suggests the possibility of targeting PPARγ to counteract age‐associated metabolic dysfunction.

Source: Aging Cell - January 31, 2018 Category: Cytology Authors: Lingyan Xu, Xinran Ma, Narendra Kumar Verma, Dongmei Wang, Oksana Gavrilova, Richard L. Proia, Toren Finkel, Elisabetta Mueller Tags: ORIGINAL ARTICLE Source Type: research