Performance of Antinuclear Antibodies for Classifying Systemic Lupus Erythematosus: A Systematic Literature Review and Meta ‐Regression of Diagnostic Data

ConclusionThe results of this systematic literature review and meta‐regression confirm that IIF‐ANAs have high sensitivity for SLE. ANAs at a titer of 1:80 have sufficiently high sensitivity to be considered as an entry criterion for SLE classification criteria, i.e., formally test other classification criteria for SLE only if ANAs of at least 1:80 have been found.

Source: Arthritis Care and Research - January 30, 2018 Category: Rheumatology Authors: Nicolai Leuchten, Annika Hoyer, Ralph Brinks, Monika Schoels, Matthias Schneider, Josef Smolen, Sindhu R. Johnson, David Daikh, Thomas D örner, Martin Aringer, George Bertsias, Tags: Original Article Source Type: research