Detecting the Presence of Bacterial DNA and RNA by Polymerase Chain Reaction to Diagnose Suspected Periprosthetic Joint Infection after Antibiotic Therapy

ConclusionsDNA‐based qPCR could detect suspected PJI with high sensitivity after antibiotic therapy. RNA‐based qPCR could reduce the false positive rates of DNA‐based assays. qPCR‐based methods could improve the efficiency of PJI diagnosis.

Source: Orthopaedic Surgery - November 1, 2017 Category: Orthopaedics Authors: Xin ‐yu Fang, Wen‐bo Li, Chao‐fan Zhang, Zi‐da Huang, Hui‐yi Zeng, Zheng Dong, Wen‐ming Zhang Tags: BASIC RESEARCH Source Type: research