Interleukin ‐10 ‐1082A/G polymorphism is associated with renal parenchymal damage in congenital anomalies of the kidney and urinary tract

ConclusionOur results suggested that the functional ‐1082A/G polymorphism in IL10 is associated with risk of renal parenchymal damage/reduction rather than genetic predisposition to CAKUT. Additionally, our study supposes that immunoregulatory cytokine IL‐10 might has significant role in CAKUT.

Source: Nephrology - January 30, 2018 Category: Urology & Nephrology Authors: Lyuba Dineva Miteva, Emilya Stambolova Kostadinova, Spaska Angelova Stanilova Tags: Original Article Source Type: research