Doxycycline attenuates chronic intermittent hypoxia ‐induced atrial fibrosis in rats

ConclusionsCIH treatment induced significant atrial fibrosis in our rat model, which was attenuated by doxycycline. These changes can be explained by alterations in the MMP and miR‐21/ERK signaling pathways.This article is protected by copyright. All rights reserved.

Source: Cardiovascular Therapeutics - January 30, 2018 Category: Cardiology Authors: Weiding Wang, Kai Zhang, Xiongfeng Li, Zuowang Ma, Yue Zhang, Meng Yuan, Ya Suo, Xue Liang, Gary Tse, Christos A. Goudis, Tong Liu, Guangping Li Tags: Original Research Article Source Type: research