Neonatal exposure to estradiol increases dopaminergic transmission in Nucleus Accumbens and morphine ‐induced conditioned place preference in adult female rats

In conclusion, neonatal programming with estradiol increases NAcc dopaminergic neurotransmission in the adulthood, which may be associated with increased reinforcing effects of drugs of abuse.
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Source: Journal of Neuroendocrinology - January 1, 2018 Category: Endocrinology Authors: Christian Bonansco, Jonathan Mart ínez‐Pinto, Roxana A. Silva, Victoria B. Velásquez, Andrés Martorell, Mónica V. Selva, Pedro Espinosa, Pablo R. Moya, Gonzalo Cruz, María Estela Andrés, Ramón Sotomayor‐Zárate Tags: Original Article Source Type: research