Monitoring of Unfractionated Heparin Using Activated Partial Thromboplastin Time: An Assessment of the Current Nomogram and Analysis According to Age

Conclusion:
Our results indicate a high rate of achieving therapeutic aPTT at 24hous and 48hours, but a low success rate for maintenance within the TR. Most patients had supratherapeutic aPTT of more than 90 seconds. Therefore, the TR of aPTT that matches heparin levels of 0.3 to 0.7 IU/mL measured by antifactor Xa assay should be determined. If not, we should consider adopting a new heparin dosing nomogram.

Source: Clinical and Applied Thrombosis/Hemostasis - August 26, 2014 Category: Hematology Authors: Kim, J. S., Lee, H. J., Sung, J. D., Kim, H.-J., Lee, S.-Y., Kim, J. S. Tags: Original Articles Source Type: research