Folate receptor α is associated with poor clinicopathological perspectives in breast carcinoma

Conclusion Our work demonstrates that FRα is over expressed in IDC compared to non- neoplastic breast tissue. Folate receptor α expression was associated with poor clinicopathological perspective. This work suggests that FRα may be an independent prognostic factor and supports the possibility of using FRα- targeted therapies of breast carcinoma. However, our work requires validation on larger cohort with correlation with survival data of patients.
Source: Pathophysiology - Category: Pathology Source Type: research