Improved nuclear delivery of antisense 2'‐Ome RNA by conjugation with the histidine‐rich peptide H5WYG

ConclusionsThe results of the present study show that the conjugation of 2'‐Ome antisense RNA to peptide H5WYG is a good strategy for improving its cytosol delivery, accumulation in the nucleus and antisense activity. Copyright © 2014 John Wiley & Sons, Ltd.

Source: The Journal of Gene Medicine - August 25, 2014 Category: Genetics & Stem Cells Authors: Ulysse Asseline, Cristine Gonçalves, Chantal Pichon, Patrick Midoux Tags: Research Article Source Type: research