[Correspondence] Reassessment of a meta-analysis of procalcitonin-guided antibiotic therapy for lower respiratory tract infections

In their meta-analysis, Phillip Schuetz and colleagues1 found a clinically significant, 30-day mortality benefit of procalcitonin-directed treatment in patients with acute respiratory infections across all treatment settings. The meta-analysis was valid and reproducible, with nearly identical control and treatment groups and attention to allocation concealment, and masked outcome assessment of the source randomised controlled trials.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research