AMPK: guardian of metabolism and mitochondrial homeostasis

Nature Reviews Molecular Cell Biology 19, 121 (2018). doi:10.1038/nrm.2017.95 Authors: Sébastien Herzig & Reuben J. Shaw Cells constantly adapt their metabolism to meet their energy needs and respond to nutrient availability. Eukaryotes have evolved a very sophisticated system to sense low cellular ATP levels via the serine/threonine kinase AMP-activated protein kinase (AMPK) complex. Under conditions of low energy, AMPK phosphorylates specific
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research