Building and decoding ubiquitin chains for mitophagy

Nature Reviews Molecular Cell Biology 19, 93 (2018). doi:10.1038/nrm.2017.129 Authors: J. Wade Harper, Alban Ordureau & Jin-Mi Heo Mitochondria produce energy in the form of ATP via oxidative phosphorylation. As defects in oxidative phosphorylation can generate harmful reactive oxygen species, it is important that damaged mitochondria are efficiently removed via a selective form of autophagy known as mitophagy. Owing to a combination of
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research