Building and decoding ubiquitin chains for mitophagy
Nature Reviews Molecular Cell Biology 19, 93 (2018).
doi:10.1038/nrm.2017.129
Authors: J. Wade Harper, Alban Ordureau & Jin-Mi Heo
Mitochondria produce energy in the form of ATP via oxidative phosphorylation. As defects in oxidative phosphorylation can generate harmful reactive oxygen species, it is important that damaged mitochondria are efficiently removed via a selective form of autophagy known as mitophagy. Owing to a combination of
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: J. Wade Harper Alban Ordureau Jin-Mi Heo Tags: Review Source Type: research