Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study)

Nasopharyngeal carcinoma (NPC) is an endemic malignancy in Southern China and South-East Asia. The mainstay treatment is radiotherapy (RT) with or without concurrent chemotherapy (CRT). Lee et al. reported the results of NPC treated in Hong Kong (HK) from 1996 to 2000 [1]. Since then, the standard care of NPC has undergone major changes in the decades that followed, which included adopting the 7th edition of the American Joint Committee on Cancer and International Union Against Cancer (AJCC/UICC) [2,3] staging system, employing magnetic resonance imaging (MRI) as standard radiological staging of loco-regional disease, adding concurrent cisplatin chemotherapy to radiation in patients with loco-regional advanced disease, and using intensity modulated radiotherapy (IMRT) as standard radiotherapy treatment.
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research