Intraoral ultrasonography to measure tumor thickness of oral cancer: A systematic review and meta-analysis

Head and neck cancer is the sixth most common malignancy worldwide of which approximately one third consists of oral squamous cell carcinoma (OSCC) [1,2]. For early OSCC (Stage I-II), surgery is the preferred treatment choice. Its complete removal is essential for locoregional control and disease-free survival [3]. Most authors agree that adequate histopathological resection margins are crucial, although it is debated how wide surgical margins should be [4 –9]. For all T-stages, free margins of at least 5 mm to the tumor invasive front are accepted as “negative” resection margins.

Source: Oral Oncology - December 18, 2017 Category: Cancer & Oncology Authors: Thomas J.W. Klein Nulent, Rob Noorlag, Ellen M. Van Cann, Frank A. Pameijer, Stefan M. Willems, Adrian Yesuratnam, Antoine J.W.P. Rosenberg, Remco de Bree, Robert J.J. van Es Tags: Review Source Type: research