Reduced white matter connectivity associated with auditory verbal hallucinations in first-episode and chronic schizophrenia: a diffusion tensor imaging study

This study aims to explore whether auditory verbal hallucinations (AVH) in schizophrenia are associated with the white matter abnormalities in tracts connecting language, auditory and memory/limbic networks in first-episode and chronic schizophrenia patients. 21 first-episode (FE-AVH) and 12 chronic (chronic-AVH group) patients who suffered from auditory verbal hallucinations and 26 healthy controls (HC group) were enrolled. Diffusion tensor imaging with tract-based spatial statistics was performed to assess the white matter changes between the two patient groups and HC group.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Source Type: research