Effect of Metformin on Glycemic Control in Patients with Type 1 Diabetes: A Meta ‐Analysis of Randomized Controlled Trials

ConclusionsCompared to placebo metformin was not associated with glycemic control in T1D patients. Although it exhibited other benefits, such as lower BMI and reduced insulin requirements, TC and LDL‐c, negative outcomes, such as gastrointestinal adverse effects and severe hypoglycemia, should also be considered in the use of metformin for T1D patients.
Source: Diabetes/Metabolism Research and Reviews - Category: Endocrinology Authors: Tags: RESEARCH ARTICLE Source Type: research