Mitochondria at the neuronal presynapse in health and disease

Nature Reviews Neuroscience 19, 63 (2018). doi:10.1038/nrn.2017.170 Authors: Michael J. Devine & Josef T. Kittler Synapses enable neurons to communicate with each other and are therefore a prerequisite for normal brain function. Presynaptically, this communication requires energy and generates large fluctuations in calcium concentrations. Mitochondria are optimized for supplying energy and buffering calcium, and they are actively recruited to presynapses.
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Review Source Type: research