Accumulation of Antigen ‐Driven Lymphoproliferations in Complement Receptor 2/CD21−/low B Cells From Patients With Sjögren's Syndrome

ConclusionClonal lymphoproliferations in patients with SS preferentially accumulate in the autoreactive CD21−/low B cell compartment often expanded in these subjects, and recognition of self antigens may drive the clonal B cell expansion while further refining BCR self‐reactivity.

Source: Arthritis and Rheumatism - January 18, 2018 Category: Rheumatology Authors: Salom é Glauzy, Marco Boccitto, Jason M. Bannock, Fabien R. Delmotte, David Saadoun, Patrice Cacoub, John A. Ice, Kathy L. Sivils, Judith A. James, Sandra L. Wolin, Eric Meffre Tags: Original Article Source Type: research