Forensic evaluation of STR typing reliability in lung cancer

Short tandem repeats (STRs), also known as microsatellites, are genomic DNA sequences that consist of repeating units (2 –6 bp) [1]. In eukaryotic genomes, STRs are extensively distributed in non-coding regions and characterized by co-dominant inheritance, high levels of polymorphisms, high reliability and good reproducibility; thus making them effective for forensic analysis [1,2]. As second generation genetic ma rks, STRs are broadly used in forensics for personal identification and paternity testing [2–4].

Source: Legal Medicine - November 11, 2017 Category: Forensic Medicine Authors: Peng Zhang, Ying Zhu, Yongguo Li, Shisheng Zhu, Ruoxiang Ma, Minzhu Zhao, Jianbo Li Source Type: research