Species-specific expression of phosphoglycerate kinase 2 (PGK2) in the developing porcine testis

Whereas stage-specific markers for spermatogonial cells have been well investigated in mouse, the specific markers of germ cells in the testis of domestic animals have not been well defined. Phosphoglycerate kinase (PGK), an enzyme that converts 1,3-bisphosphoglycerate and adenosine diphosphate to 3-phosphoglycerate and adenosine triphosphate, has two isozymes: PGK1 and PGK2. In mouse, PGK1 exists only during the early stages of spermatogenesis, and PGK2 is then expressed during the pachytene spermatocyte stage.

Source: Theriogenology - January 17, 2018 Category: Genetics & Stem Cells Authors: Hyun-Jung Park, Won-Young Lee, Chankyu Park, Kwon-Ho Hong, Jin-Hoi Kim, Hyuk Song Source Type: research