Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass

This study showed that Areg mRNA expression was significantly up‐regulated in obese adipose tissues and over‐expression of Areg in white adipose tissue caused less adipose tissue mass. Areg mRNA expression was significantly up‐regulated in mouse obese adipose tissues, and over‐expression of Areg in white adipose tissue caused less adipose tissue mass.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fgtc.12558

Source: Genes to Cells - January 1, 2018 Category: Genetics & Stem Cells Authors: Bo Yang, Takahiro Kumoto, Takeshi Arima, Minako Nakamura, Yohei Sanada, Thanutchaporn Kumrungsee, Yusuke Sotomaru, Masayuki Shimada, Noriyuki Yanaka Tags: ORIGINAL ARTICLE Source Type: research

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