Correlation between epidermal growth factor receptor and MIB-1 index in different grades of astrocytomas

Conclusion A significant correlation was found between EGFR overexpression and MIB-1 LI in grade II, grade III, and gliobastoma multiform. These may suggest that tumor proliferation, at least in the higher grades of astrocytomas, depends up to some extent on epidermal growth factor and EGFR-related signaling pathways.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research