The role of immunohistochemical expression of OCT-4 and SOX2 as predictors of recurrence and progression in superficial urinary bladder carcinoma

Conclusion The present study reveals that tumor size is an important clinical risk factor for tumor recurrence and progression. Positive OCT-4 expression may be a predictive marker in NMIBC progression. More prospective studies on different stages of UBC are needed to clarify the potential role of OCT-4 in the biology and behavior of UBC. However, SOX2 has limited role in early-stage bladder cancer.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research