Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein ‐2 deficiency

Conclusions: These data prove that the peroxisomal β‐oxidation pathway is required within Purkinje neurons to maintain their axonal integrity, independent of glial dysfunction. This article is protected by copyright. All rights reserved.

Source: Brain Pathology - January 1, 2018 Category: Neurology Authors: Stephanie De Munter, Dorien Bamps, Ana Rita Malheiro, Ritesh Kumar Baboota, Pedro Brites, Myriam Baes Tags: Research Article Source Type: research