The impact of butorphanol in rat temporomandibular joint inflammation

The objective of the present study was to evaluate the anti-inflammatory effect of butorphanol in formalin-induced temporomandibular joint (TMJ) inflammation in rats. Materials and methods A total of 30 adult male Wistar rats were randomly divided into three groups of 10 rats each – group 1, the saline control group: rats were subjected to TMJ injection of saline; group 2, the formalin control group: rats were subjected to TMJ injection of formalin and did not receive any treatment; group 3, the butorphanol-treated group: rats received TMJ injection of 0.4 mg/kg butorphanol 30 min after TMJ injection of formalin. Results TMJ injection of 1.5% formalin-induced inflammation in the form of significant (P
Source: Egyptian Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Tags: Original Articles Source Type: research