Loss of VAMP5 in mice results in duplication of the ureter and insufficient expansion of the lung

Conclusions: VAMP5 KO mice showed a low birth rate and abnormalities of the urinary and respiratory systems. VAMP5 KO mice died around birth, possibly due to defects in vesicoureteral flow and breathing. The results presented could provide a basis for future studies to understand the roles of VAMP5 protein. This article is protected by copyright. All rights reserved.

Source: Developmental Dynamics - January 13, 2018 Category: Molecular Biology Authors: Maiko Ikezawa, Yuki Tajika, Hitoshi Ueno, Tohru Murakami, Naokazu Inoue, Hiroshi Yorifuji Tags: Patterns & Phenotypes Source Type: research