Utility of the Abbott RealTime HCV Genotype Plus RUO Assay Used in Combination with the Abbott RealTime HCV Genotype II Assay

Hepatitis C virus (HCV) can be classified into 7 genotypes (GTs) and 67 subtypes (STs) [1]. In this era of direct-acting antiviral (DAA) therapy for chronic HCV infection, accurate HCV GT determination and ST differentiation (1a versus 1b) remain important factors in the selection of appropriate DAA therapy [2 –5]. The Abbott RealTime HCV Genotype II assay (HCVGT II; Abbott Molecular Inc., Des Plaines, IL), targeting the 5’untranslated (UTR) and nonstructural (NS)5 B regions of the HCV genome, is an HCV genotyping assay approved for in vitro diagnostic use in the U.S.

Source: Journal of Clinical Virology - January 12, 2018 Category: Virology Authors: Chao He, Jeffrey J. Germer, Elizabeth R. Ptacek, Carl E. Bommersbach, P.Shawn Mitchell, Joseph D.C. Yao Tags: Short communication Source Type: research