Polypoidal Choroidal Vasculopathy

Polypoidal choroidal vasculopathy (PCV) is an age-related macular degeneration (AMD) subtype and is seen particularly in Asians. Previous studies have suggested disparity in response to intravitreal injections of anti –vascular endothelial growth factor (VEGF) agents between PCV and typical AMD, and thus, the preferred treatment for PCV has remained unclear. Recent research has provided novel insights into the pathogenesis of PCV, and imaging studies based on OCT suggest that PCV belongs to a spectrum of condit ions characterized by pachychoroid, in which disturbance in the choroidal circulation seems to be central to its pathogenesis.

Source: Ophthalmology - January 10, 2018 Category: Opthalmology Authors: Chui Ming Gemmy Cheung, Timothy Y.Y. Lai, Paisan Ruamviboonsuk, Shih-Jen Chen, Youxin Chen, K. Bailey Freund, Fomi Gomi, Adrian H. Koh, Won-Ki Lee, Tien Yin Wong Source Type: research