A brief report of Plexiform Neurofibroma

Plexiform Neurofibroma (PNF) is a rare variant of Neurofibromatosis type1(NF-1), which histopathologically, is a subtype of benign nerve sheath tumors, Neurofibromas (NF). It develops as a result of proliferation in all parts of peripheral nervous system and can cause the functional damage, deformities, pain, considerable mortality and morbidity and even the increasing risk of malignant transformation in some critical cases. Currently, the surgical intervention is the treatment of choice for PNF patients, which due to the tumor invasion, massive growth and the chance of postoperative regrowth is not possible.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Source Type: research