Preliminary mapping of the structural effects of age in pediatric bipolar disorder with multimodal MR imaging

This study investigates multimodal structural MR imaging biomarkers of development trajectories in pediatric bipolar disorder. T1-weighted and diffusion-weighted MR imaging was conducted to investigate cross-sectional group differences with age between typically developing controls (N=26) and youths diagnosed with bipolar disorder (N=26). Region-based analysis was used to examine cortical thickness of gray matter and diffusion tensor parameters in superficial white matter, and tractography-based analysis was used to examine deep white matter fiber bundles.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Source Type: research