Methotrexate free chemotherapy and limb salvage surgery for paediatric osteosarcoma in India

Conclusions: High dose methotrexate free chemotherapy can give good OAS in localized disease and LSS is feasible in most of the pediatric OS patients. However the modest DFS even for localized disease with PAI chemotherapy and extremely poor outcomes in the metastatic OS, demand further research and innovations in systemic therapy to improve outcomes.

Source: Indian Journal of Orthopaedics - January 10, 2018 Category: Orthopaedics Authors: Reghu Kesavapillai Sukumaran Binitha Rajeshwari Subin Sugath S Guruprasad Chellappan Priyakumari Thankamony Kusumakumary Parukuttyamma Source Type: research