Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease [Original Articles]

Conclusions These results suggest a significant polygenic contribution in individuals presenting with EOCAD, which could be more prevalent than familial hypercholesterolemia. Determination of the polygenic risk component could be included in the diagnostic workup of patients with EOCAD.

http://circgenetics.ahajournals.org/cgi/content/short/11/1/e001849?rss=1

Source: Circulation: Cardiovascular Genetics - January 8, 2018 Category: Cardiology Authors: Theriault, S., Lali, R., Chong, M., Velianou, J. L., Natarajan, M. K., Pare, G. Tags: Epidemiology, Risk Factors, Genetics, Coronary Artery Disease Original Articles Source Type: research