Use of darbepoetin to stimulate erythropoiesis | of chronic kidney disease in Dogs

Chronic kidney disease (CKD) is a metabolic disorder of companion animals, estimated to occur in 0.4 to 1.5% of dogs and represented in a higher percentage of older dogs and those evaluated at tertiary care facilities. A progressive, normocytic, normochromic, hypoproliferative anemia develops as a feature of CKD, and although there are no published data on the prevalence of anemia in dogs with CKD, it is expected to occur in most dogs that progress to end-stage disease. Although the pathogenesis of the anemia of CKD is multifactorial, decreased production of erythropoietin by the diseased kidneys is an important factor.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Nephrology/Urology Source Type: research