Switched Memory B Cells Are Increased In Oligoarticular And Polyarticular Juvenile Idiopathic Arthritis And Their Change Over Time Is Related To Response To TNF Inhibitors

ConclusionsSwM B‐cells expand during disease course in JIA patients at a faster rate than in healthy children. This increase is more evident in early‐onset JIA; TNFi treatment inhibits this increase in patients who achieve and maintain remission, but not in those with active diseaseThis article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatism - January 1, 2018 Category: Rheumatology Authors: Emiliano Marasco, Angela Aquilani, Simona Cascioli, Gian Marco Moneta, Ivan Caiello, Chiara Farroni, Ezio Giorda, Valentina D'Oria, Denise Pires Marafon, Silvia Magni ‐Manzoni, Rita Carsetti, Fabrizio De Benedetti Tags: Full Length Source Type: research