Detecting Mycobacterium tuberculosis complex DNA, based on post-mortem examination of hilar lymph nodes with real-time PCR: initial study.

CONCLUSIONS: Real-time PCR Xpert MTB/RIF was capable of detecting M. tuberculosis complex DNA in a patient with tuberculosis recognised on autopsy. In the remaining patients, no M. tuberculosis complex DNA was found, in accordance with negative results of histological examination. Since the technology of cartridges has changed, it is no longer possible to use real-time PCR Xpert MTB/RIF (Cepheid USA) on post-mortem material.
PMID: 25133811 [PubMed - in process]

Source: Pneumonologia i Alergologia Polska - August 20, 2014 Category: Respiratory Medicine Authors: Rzechorzek W, Szańkowska M, Szczepankiewicz B, Cyran-Chlebicka A, Safianowska A Tags: Pneumonol Alergol Pol Source Type: research