Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities

CONCLUSIONSModerate‐to‐severe GCA is most likely to occur in the presence of AD or CVD and should not be solely attributed to age when evaluating clinical imaging findings in the workup of cognitive complaints. Developing optimal diagnostic and treatment strategies for cognitive decline in the setting of GCA requires an understanding of its risk factors in the aging population.

Source: Journal of Neuroimaging - January 1, 2018 Category: Radiology Authors: Omar M. Al ‐Janabi, Pradeep Panuganti, Erin L. Abner, Ahmed A. Bahrani, Ronan Murphy, Shoshana H. Bardach, Allison Caban‐Holt, Peter T. Nelson, Brian T. Gold, Charles D. Smith, Donna M. Wilcock, Gregory A. Jicha Tags: Clinical Investigative Study Source Type: research